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Procell Inc human crc cell lines dld1
Human Crc Cell Lines Dld1, supplied by Procell Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human crc cell lines dld1/product/Procell Inc
Average 90 stars, based on 1 article reviews
human crc cell lines dld1 - by Bioz Stars, 2026-03
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Venn diagram of curcumin targets, CRC-related genes, and DEGs from curcumin-treated DLD1 cells.

Journal: Frontiers in Pharmacology

Article Title: Integrated network pharmacology and experimental verification to reveal the mechanisms of curcumin in the treatment of colorectal cancer

doi: 10.3389/fphar.2025.1703562

Figure Lengend Snippet: Venn diagram of curcumin targets, CRC-related genes, and DEGs from curcumin-treated DLD1 cells.

Article Snippet: The human CRC cell line DLD1 (ATCC, United States) was cultured as described and seeded in 96-well plates to reach 80% confluence before treatment.

Techniques:

Curcumin promotes ferroptosis and regulates Wnt/β-catenin signaling pathway in vitro . (A) Representative images of transmission electron microscopy observation of mitochondria; curcumin induced reduced mitochondrial volume and increased membrane density in HCT116 cell lines (scale bar: 2 μm and 500 nm); (B) Relative mitochondrial area in HCT116 cell lines. (C) Relative mitochondrial density in HCT116 cell lines. (D–E) Curcumin induced the accumulation of Lipid ROS in CRC cells. Dose-dependent accumulation of Lipid ROS in HCT116 and DLD1 cells treated with curcumin (5–20 μm). (F–G) Curcumin effectively inhibited the expression of SLC7A11 and GPX4, downregulated level of β-catenin and promoted phosphorylation of GSK3β at Ser9. *P < 0.05, **P < 0.01 and ***P < 0.001.

Journal: Frontiers in Pharmacology

Article Title: Integrated network pharmacology and experimental verification to reveal the mechanisms of curcumin in the treatment of colorectal cancer

doi: 10.3389/fphar.2025.1703562

Figure Lengend Snippet: Curcumin promotes ferroptosis and regulates Wnt/β-catenin signaling pathway in vitro . (A) Representative images of transmission electron microscopy observation of mitochondria; curcumin induced reduced mitochondrial volume and increased membrane density in HCT116 cell lines (scale bar: 2 μm and 500 nm); (B) Relative mitochondrial area in HCT116 cell lines. (C) Relative mitochondrial density in HCT116 cell lines. (D–E) Curcumin induced the accumulation of Lipid ROS in CRC cells. Dose-dependent accumulation of Lipid ROS in HCT116 and DLD1 cells treated with curcumin (5–20 μm). (F–G) Curcumin effectively inhibited the expression of SLC7A11 and GPX4, downregulated level of β-catenin and promoted phosphorylation of GSK3β at Ser9. *P < 0.05, **P < 0.01 and ***P < 0.001.

Article Snippet: The human CRC cell line DLD1 (ATCC, United States) was cultured as described and seeded in 96-well plates to reach 80% confluence before treatment.

Techniques: In Vitro, Transmission Assay, Electron Microscopy, Membrane, Expressing, Phospho-proteomics